Apport de l’angiomammographie dans le bilan pré-thérapeutique du cancer du sein localisé / Fanny Montrognon ; sous la direction de Florian Clatot et de Françoise

Date :

Type : Livre / Book

Type : Thèse / Thesis

Langue / Language : français / French

Mammographie

Cancer du sein

Angiographie

Clatot, Florian (1979-...) (Directeur de thèse / thesis advisor)

Callonnec, Françoise (1964-....) (Directeur de thèse / thesis advisor)

Savoye-Collet, Céline (1969-.... ; Enseignante-chercheuse) (Président du jury de soutenance / praeses)

Vera, Pierre (1964-.... ; enseignant-chercheur en biophysique et traitement de l'image) (Membre du jury / opponent)

Relation : Apport de l’angiomammographie dans le bilan pré-thérapeutique du cancer du sein localisé / Fanny Montrognon ; sous la direction de Florian Clatot et de Françoise / Rouen : SCD de l'Université de Rouen , 2022

Résumé / Abstract : Objective: A precise evaluation of the disease extent is mandatory before surgery for early breast cancer (EBC). Contrast-enhanced mammography (CEDM) is a recent technique that may help define adequate surgery. Methods: This retrospective study included consecutive patients referred to a cancer center between November 2016 and July 2017 for biopsy-confirmed invasive EBC management. The primary objective was to evaluate the rate of surgical changes after incorporating the results of the preoperative staging examination, including CEDM. Results: A total of 231 patients were screened for inclusion, and 132 patients were included, corresponding to 134 lesions. The first surgical plan was modified for 33 patients (25%), which represented 34 lesions. For 8 patients (6%), the surgery was cancelled in preference for neoadjuvant chemotherapy; for 16 patients (12.1%), the primary tumor procedure was enlarged; and for 23 patients (17.4%) the lymph node management was modified. Surgery was changed only due to the CEDM results for 24 patients (18.5%) and consisted of a more invasive procedure due to a more extended, multifocal or multicentric lesion than seen on the standard imaging. Anatomopathological surgery piece findings were well correlated with contrast-enhanced mammography results. Overall, there was no increase in the delay between the planned date of surgery and the effective surgical procedure (median 0 days). Conclusion: CEDM added to preoperative staging helped define better surgical management without increasing delay in the surgical procedure.